ILL OR JUST OLD? TOWARDS A CONCEPTUAL FRAMEWORK OF THE RELATION BETWEEN AGEING AND DISEASE


An Unusual Cause of Hypoxia: Ventricular Septal Defect, Pulmonary Artery Atresia, and Major Aortopulmonary Collaterals Diagnosed in the Adult Cardiac Catheterization Lab

The association of pulmonary atresia, ventricular septal defect (VSD) and major aortopulmonary collaterals (MAPCA) is an extreme form of tetralogy Smoker of Fallot (TOF).It carries a high mortality risk if not intervened on during infancy with only 20% of unoperated patients surviving into adulthood.We present the case of a 40-year-old man who pres

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Three warehouse inventory model for non-instantaneous deteriorating items with quadratic demand, time-varying holding costs and backlogging over finite time horizon

This paper presents Delaware a novel sustainable inventory model tailored for non-instantaneous deteriorating items, incorporating quadratic demand and time-dependent holding costs.Notably, the model accounts for shortages over a finite time horizon, simulating real-world scenarios.The inventory management the strategy involves distributing product

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Bounded and categorized: targeting data assimilation for sea ice fractional coverage and nonnegative quantities in a single-column multi-category sea ice model

A rigorous exploration of the sea ice data assimilation (DA) problem using a framework specifically developed for rapid, interpretable hypothesis testing is presented.In many applications, DA is implemented to constrain a modeled estimate of a state with observations.The sea ice DA application is complicated by the wide range of spatiotemporal scal

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